Sentence examples for hubs of miRNA from inspiring English sources

We found a repertoire of miRNAs downregulated in MDD along with related gene-targets and gene "hubs" of miRNA activity.

Finally, our data indicates that some genes may serve as hubs of miRNA activity.

Shalgi et al [24] identified genes as "hubs" of miRNA regulation that were under the post-transcriptional regulation of dozens of miRNAs.

However, the σ RF of miRNA out-hubs fluctuates around zero.

Altogether, this work highlights the potential of miRNA functional studies to decipher cell signalling pathways or major regulatory hubs involved in cell survival to finally propose the rationale design of new strategies on the basis of pharmacological combinations.

This review revisits the discovery of miRNA, examines the possibility of miRNA biomarkers, discusses the conventional methods and emerging techniques for miRNA detection and quantification, and postulates future prospects in connection to electrochemical detection and quantification of miRNAs.

Normalized abundance of miRNA reads.

Jessica had remained in Sydney and was visiting Jakarta at the time of Mirna's death.

Indeed, as it is well accepted that miRNAs control functional organized networks, it is tempting to speculate that the nodes or hubs of important regulatory pathways targeted by the miRNAs might constitute pertinent targets for therapeutic intervention.

We started with the difference (Ds) between mean miRNAs number (virus type) of hubs and non-hubs and then shuffled the number of miRNAs (virus type) between all nodes and re-computed the difference (Dr) between hubs and non-hubs.

First, to inspect whether the targets of herpesvirus miRNAs cover more hubs than random conditions, the statistical significance of the proportion of miRNA-targeted hubs (bottlenecks) was tested.