Sentence examples for hub cell from inspiring English sources

In Drosophila testis, a group of 8 12 GSCs reside in a niche comprised of two types of somatic cells: hub cell and cyst stem cells (CySCs).

Mapping of islet functional architecture revealed the presence of hub cells with pacemaker properties, which remain stable over recording periods of 2 to 3 hr.

Once specified, the hub cells need to maintain their position and architectural integrity through embryonic, larval and pupal stages of testis organogenesis and during adult life.

In male GSCs, the centrosomes are stereotypically oriented toward the adherens junction between the GSCs and hub cells, preparing for spindle orientation perpendicular to the hub cells.

Nevertheless, GSCs expressing E-caddCR4h remattachedtoched thethubhub cells, presumably because hub-GSC interactions were supported by endogenous E-cadherin (Figure 1A).

We found that E-cadherin is indeed required for polarizing GSCs toward the hub cells, an effect that may be mediated by Apc2.

We speculate that E-caddCR4h-expressing GSCs may need a larger cortical area to stay adhered to the hub cells due to its disadvantage in adhesion.

In cnn mutant, extra GSCs were observed to be "over-crowded" around the hub cells, attaching to the hub with a small cortical area, since the hub size does not increase.

In the male germ line, Dnmt2-EGFP was expressed in most cells, including stem cells as well as in maturing spermatocytes (Fig. 2E) with the exception of the post-mitotic hub cells (Fig. 2G).

We propose that the adherens junction formed between the niche component (hub cells) and stem cells (GSCs) serves as a platform for multiple functions essential for stem cells: 1) maintenance of stem cells within the niche by physically anchoring the stem cells, 2) polarization of stem cells with respect to the niche, and 3) localization of factor(s) required for monitoring stem cell polarity.

The highly connected "hub cells" may be a different population of cells from the "trigger cells" driving the network activity.