The delivery efficiencies of PTDs are, however, often poor because PTD-protein conjugates cannot escape from endosomes.
Genomic instability and the evolution of aneuploid cell lineages are a hallmark of many cancers; therefore, DNA content is an important measure of intra-tumoural genetic heterogeneity, which is, however, often neglected because of not being directly visible in the analysis of complex tumour samples.
Hypertension in adolescents however often goes undiscovered because adolescents are generally healthy and visit a physician only when they are very ill.
The benefits from trees and their genetic resources are, however, often not well quantified because trade is frequently outside formal markets, there is a multiplicity of species and ways in which trees are used and managed, and genetic diversity within species is frequently not given proper consideration.
This is, however, often a major problem because of difficulties to access the tissue or to culture this cell type ex vivo.
Variables measured over time, however, often violate this assumption because they exhibit 'autocorrelation' in the form of secular trends, cycles, or the tendency to remain elevated or depressed, or to oscillate, after high or low values.
The species that starts closest to the optimum, however, often benefits from competition, because the selection induced by the moving optimum is augmented by selection in the same direction caused by competition, the net effect of which is a reduced lag and an increase in time to extinction.
However, often controversial conclusions were drawn because of the inability to distinguish between auto- and allosyndetic pairing at meiosis.
There's a price to pay, however, because often fat asparagus must be peeled, from the base of the flower to the end of the stalk.
However, difficulties often arise because development is defined implicitly.
