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However, many agents that appeared to be promising in preclinical studies have failed to show efficacy in clinical trials.
Consider getting an agent, however many agents can be very deceiving, so be careful.[citation needed].
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There is no specific therapy for HUVS; however, many therapeutic agents have been found to be beneficial.
However, many anticancer agents exhibit high BSV, and PK evaluations in clinical trials are often sparse.
However, many zoonotic agents can be difficult to exclude from even meticulously controlled breeding facilities (3, 5 ).
However, many antiretroviral agents [ 18, 19] have been investigated as CYP3A4, 2B6, or 2D6 strong inducers or inhibitors.
To date, however, many such agents are nontargeted and rely on a passive transvascular delivery into the solid tumors, resulting in difficulties translating the efficacies found in vitro and in animal models into the clinic.
7 The cardiac effects of the anthracyclines are the most studied among antineoplastic agents; however, many other treatments—such as alkylating agents, vinca alkaloids, antimetabolites, and biological agents—are also recognised to have long term cardiac sequelae.
However, many of these agents are still waiting well-designed clinical studies in order to prove their beneficial therapeutic role.
However, many host-targeted agents are natural products, which can be difficult to optimize using synthetic chemistry alone.
However, many of the agents currently being evaluated have multiple targets and their antitumor effects may not be due to K-Ras inhibition.
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CEO of Professional Science Editing for Scientists @ prosciediting.com