Sentence examples for however, a significant issue from inspiring English sources

However a significant issue is that even such an experiment would require high index prisms for in and out-coupling which are not readily available in the visible range.

However, a significant issue of concern in performing any contouring algorithm is the initialization of the contour, especially for the case of liver segmentation, where other organs in close proximity have similar intensity distributions.

However, this is a significant issue since it has an essential role in DNA replication.

"But it still is a significant issue.

However, running time was a significant issue right from the beginning of the matching process.

Fluid prokaryotic genomes, however, appear not to be a significant issue for identifying plastid-derived genes.

However, this did not emerge as a significant issue as the interview data and the opinions expressed were overall very honest and open.

"I have received a volume of correspondence from constituents objecting to the changes it is a significant issue in this election, however the dilemma is to identify another area of revenue to target," Goodenough said.

It is hard to know for sure, however, and relatively few Republicans regard gun violence as a significant issue.

However, the cost effectiveness of the majority of AVC mitigation measures is a significant issue.

However, Lauderdale was disliked for his opposition to the popular Queen Caroline, which became a significant issue in the campaign.