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The mechanisms of how these altered genes contribute to the decreased malignancy of A2058 cells remain unclear and require further examination in the future.
They are used to understand how transcripts are altered by diseases such as cancer and how these altered transcripts play a significant role in distinguishing cancer and its subtypes (88).
Little is known about how these altered conditions affect important aspects of forest recovery such as the establishment of new tree biomass and species composition.
It remains unclear whether and how these altered methylation profiles directly affect the expression profiles of the imprinted genes Slc22a2, and Slc22a3 and that of the non-imprinted Slc22a1 gene.
However, the next section describes how these altered p-values were used in modified adjustments for multiple testing.
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This study aims (1) to define the limits of the normal human conjunctival fornices and how these alter with age and (2) to provide normative data for upper and lower fornix depths (FDs) and fornix intercanthal distance (FICD) within a healthy South Asian, racially distinct population.
Whether specific local selective pressures by antimicrobials may have contributed to the changes described above, and how these alter antimicrobial resistance, remains to be determined.
For example, they should facilitate opportunities for patients to express information about their illness that include the centrality of meanings shaped by religious beliefs, and how these alter their perceptions of illness and quality of life [ 41].
It explains the structure/function relationship between the various regions of the aggrecan molecules and how these are altered by synthetic and catabolic events that occur throughout life and in the diseased joint.
This chapter discusses the normal mitochondrial structure and function and how these are altered in amyotrophic lateral sclerosis (ALS) and what evidence there is that the resultant mitochondrial dysfunction contributes to disease pathogenesis in ALS.
We carried out a quantitative and qualitative appraisal of selected EGS (timber production, carbon stock, provision of water, water regulation, biodiversity, and forage production) to understand how these have altered in a complex mosaic of landscape that has undergone significant change over the past 200 years.
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