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Daly has skills to complement those of his outside-half, and while forceful runners are valuable in phase play, passing counts in set-piece moves, an area where Jones, who has pointed out how sequence play has become last year's thing, will be focusing on in the next two weeks.
We introduce an example to ease the understanding of how sequence mining could be used with scientific workflows.
Our results show how sequence inversion confers a distinctive peptide surface behaviour and lipid interaction for molecules with a similar structure.
In complementary work we show how sequence motifs characteristic of allergenic proteins in protein families can be used as fingerprints for allergenicity.
An X-ray crystal structure of the K86R/G100T mutant protein bound to a DNA duplex containing the C G+4 substitution suggests how sequence specificity of a homing enzyme can increase.
The membrane-associated folding/unfolding of pH (low) insertion peptide (pHLIP) provides an opportunity to study how sequence variations influence the kinetics and pathway of peptide insertion into bilayers.
We show how sequence analysis of ChIP-Seq data derives novel biological knowledge on multiple levels, from individual transcription factor binding sites to genome segments operating as regulatory modules.
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These findings offer new insights into the underlying transcriptional circuitry of psoriasis lesions, and demonstrate how sequence-specific TF/uDBP-DNA interactions can be exploited to support dODN drug development and enhance interpretation of non-coding GWAS signals.
These results provide yet another example of how sequence-optimized constructs can be powerful tools in functional genomics.
Taken together these results support a new paradigm for how sequence-degenerate single-stranded genetic material is recognized and exchanged between bacteria.
Specifically, I propose that two aspects of how sequence-folding-structure relationships are taught distract students from learning the phenomena that underpin protein folding: 1.
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