Given that the CTF also exists in neurons and is toxic when having expanded polyQ, it would be particularly important to identify its area of expression in normal brains and how it is altered in SCA6.
Money is a recurring trope here — how he has it and how it's altered his perspective.
Biomarkers are proposed to measure the delivery of drugs to their intended targets, and to understand and predict pathophysiology, and how it is altered by therapy, through monitoring variables known to have chemical relevance.
These two characteristics defy the classical object-observer duality, making BMIs particularly appealing for investigating how information is encoded and decoded by neural circuits in real time, how this coding changes with physiological learning and plasticity, and how it is altered in pathological conditions.
A detailed understanding of TRAIL gene upregulation will be better defined how TRAIL is utilized by the immune system and how it is altered in diseases.
3, 6 This review will focus specifically on the kidneys' role in glucose reabsorption, how it is altered in diabetics, and how it is an advantageous target for the treatment of diabetes.
Considering that TPPP may exert various physiological functions through its GTPase activity [ 9, 21], it is particularly important to confirm the location where TPPP is normally expressed, and how it is altered in each disease.
Conservators, on the other hand, scientifically analyze a painting's materials: What it's made of, how those materials have aged, whether it was altered.
Best of all, there is the wild tale of how "Halleluljah" became his biggest hit, though it has been interpreted as everything from raw erotica to Christmas carol to elevator music, depending on who performs it and how much it is altered.
