In the last years, several reports have established the notion that metabolism is not just a housekeeping process, but instead an active effector of physiological changes.
The new findings, reported in the current issue of the Journal of Clinical Investigation, suggest that the main attackers, called astrocytoma cells, flourish by exploiting the immune system's own housekeeping process.
Plus, making the housekeeping process fun for your children is crucial to getting them more involved in helping you avoid it and what better way than to let them name your new pets?! School papers, bills, coupons, fliers and forms are constantly streaming into the house.
Autophagy is a housekeeping process that ensures the turnover of damaged protein aggregates and organelles to maintain cell homeostasis [ 56].
In the heart, autophagy is an important housekeeping process that is essential for maintaining cardiac health [ 162].
Autophagy is viewed as a housekeeping process to maintain cellular homeostasis and is essential for the removal of protein and lipid aggregates, damaged and unwanted organelles.
Notably, the 94 genes translated less efficiently following depletion of eIF4G tended not to encompass essential genes, and several housekeeping processes, such as DNA processing and protein modification were underrepresented in this group.
It involves a large number of largely uncharacterized genes, which are predicted to be associated with general housekeeping processes such as transcription, translation, protein processing, signalling, cell cycle regulation, lipid metabolism, organelle transport and vesicle trafficking.
These findings suggest that under conditions of eIF4G down-regulation, a select group of mRNAs whose products function in housekeeping processes such as transcription and DNA processing, are translated relatively better than all other mRNAs; whereas a group of non-essential genes involved in cellular energy production are translated relatively worse.
The results of this analysis highlighted that the skin transcriptome presented the most distant fingerprint from the global set, since the categories related to housekeeping processes (i.e. protein fate, cell cycle and DNA processing) were under-represented while those related to secondary, amino acid and lipid metabolism were highly expressed, if compared to pulp and seeds [ 17].
The skin transcript expression profile presented the most distant fingerprint from the global set, wherein the categories related to housekeeping processes, such as protein fate, cell fate, cell cycle and DNA processing, protein synthesis and activity, were under-represented.
