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Thus, protein quality and quantity in all cellular compartments must be carefully managed both as a critical housekeeping function and to protect cellular integrity during proteotoxic stress.
P5CS2 (At3g55610) expression was consistent with a housekeeping function, and the P5CS2 protein was found to be localised in the cytosol under normal conditions while being partially re-located to plastids during stress [ 3, 8, 9].
Interestingly, two distinct classes of genes are documented to perform different functions [ 43], which low-CpG genes are mainly involved in housekeeping function and high-CpG genes are involved in development.
It is conceivable that given their housekeeping function and ubiquitous expression pattern, hence commonly open chromatin status, these genes may be more vulnerable to uptake de novo retrotransposition events.
Autophagy has a housekeeping function and is involved in cytoplasmic homeostasis as it controls the turnover of long-lived proteins, eliminates unwanted and damaged organelles and molecules and produces amino acids when nutrients become limited.
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These compounds are categorized into primary and secondary metabolites, where the former are involved in housekeeping functions and the latter are used by plants in interactions with their environment [1].
These different regulations imply that COX1- and COX2-dependent PG productions will be primarily required for housekeeping functions and rapid adaptation to various stimuli, respectively.
The remaining 25% of selected genes encoded well-characterized enzymes of central metabolism (housekeeping functions) and a small number (37) of light perception genes.
The core genome is enriched for genes in housekeeping functions and in particular for metabolic genes which are entirely missing among the strain-specific genes.
Chromosome I is thought to code mainly housekeeping functions and chromosome II is regarded to harbor virulence-related functions that are differentially expressed during adaptation to the replicative niche inside cells [18].
As highly conserved proteins are likely to encode essential housekeeping functions, and therefore be subject to high levels of purifying selection, the noted correlation between the taxonomic range and QIPP score can be explained within this selective framework.
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