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The hourly data also showed that afternoon rush hour concentrations were frequently over-predicted.
All the babies with high 24-hour concentrations then had "random" values above this cut off line, i.e. its positive predictive value for babies with 24 hour concentrations <1 mg/l was 100%.
24 hour concentrations of >1 mg/L were considered high, and an indication to extend the dosing interval.
Equally those with less good renal function would have had a lower clearance of gentamicin and high "random" and 24 hour concentrations.
If this regression line were to be used as the cut off for predicting 24 hour concentrations, its sensitivity would be 84% (16/19), positive predictive value 64% (16/25) and specificity 71% (22/31).
In our study, we did not observe any effect of malnutrition on 2 hour concentrations, Cmax, Tmax, and AUC0 4 of isoniazid, rifampicin, pyrazinamide or ethambutol, even with enhanced dosing.
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Of the 12 dogs with Cmax at 12 hours, the reported Cmax ranged from 51%to98%8% of the 12 hour concentration: 5 were at > 90%, 8 were > 80%, 10 were > 75% of the 12 hour concentration.
Table 1 shows the distribution of the mortality by cause, together with the distribution of the weather variables and PM2.5 that had a median 24 hour concentration of 34μg/m.
The judges rejected a challenge from the American Petroleum Institute, ruling that both science and the law justified a 2010 decision by the Environmental Protection Agency to limit maximum one-hour concentrations of nitrogen dioxide in the atmosphere to 100 parts per billion.
62 (87%) of 71 preterm babies had high 24-hour concentrations.
For ethambutol, 55.9% of the children had inadequate 2-hour concentrations.
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CEO of Professional Science Editing for Scientists @ prosciediting.com