To explore the precise role of BbCRASP-2 in B. burgdorferi infectivity of a mammalian host, we assessed how targeted deletion of BbCRASP-2 in an infectious isolate influences B. burgdorferi infection in the murine model of Lyme borreliosis.
To investigate the potential effects of early chronic transplantation on host parameters we assessed lesion volume, spared tissue volume, and glial scar area using methodology that we have previously employed that detected differences between complement knockout and wild type mice [28].
To investigate whether induced SCRaMbLE of a synthetic chromosome in vivo can enhance a host for biosynthesis, we assessed production of a secondary metabolite using the pigment-producing violacein biosynthesis pathway from Chromobacterium violaceum15.
Consequently, we chose simple functions to describe the constitutive fitness costs of physiological and behavioral adaptations to host defenses and we assessed the robustness of model predictions to the shape of these functions.
In order to better understand periparasitic events characterizing the host response to infection, we assessed the gene expression profile in the periparasitic liver tissue during early chronic AE.
We assessed whether host genotype could modulate water deficit effects on a gall-inducing aphid, Phloeomyzus passerinii, developing on poplars, which are known to be among the most susceptible trees to water deficit.
The rationale underlying the use of biomarkers is that since exorbitant amounts of cytokines have adverse effects on the body that lead to fatality, by measuring proinflammatory and anti-inflammatory cytokines as a degree of the inflammatory response of the host, we can assess the patients' mortality [ 52, 64– 64].
Structural variation across host gender: We further assessed microbial structure variation with respect to host gender.
To assess the impact of Zfp335R1092W on naïve T cell homeostasis, we adoptively transferred blt/ blt peripheral T cells together with wild-type controls into congenic lymphoreplete hosts and assessed their relative maintenance over 7 days.
The symbiotic effects on the vegetative growth of the hosts were assessed by total increased fresh weight and dry biomass of the plantlets.
