Sentence examples for host target from inspiring English sources

In this manner, viral RNAs de-repress and rescue the expression of host target mRNAs.

This similarity in binding surfaces permits the pathogenic protein to compete with a host target protein.

Up-regulation of host target genes would contribute to enhanced HBV expression and replication, persistent viral infection, and HCC development.

The mechanism of action was discovered to be a host target: the lipid kinase phosphatidylinositol 4-kinase III beta (PI4KIIIß).

TAL (transcription activator-like) effectors from Xanthomonas bacteria activate the cognate host genes, leading to disease susceptibility or resistance dependent on the genetic context of host target genes.

It has also been shown that diketo acid inhibitors bind to the strand transfer complex of integrase and are competitive with the host target DNA.

When viral RNAs are highly produced during HBV infection, the repression of host target genes conferred by these common miRNAs can be diluted as viral RNAs down-regulate common miRNAs.

This yielded host target-inhibitor combinations for dual specificity phosphatases (DUSPs) involved in the control in bacterial infections.

We present a strategy that integrates chemical (compound) and genetic (siRNA) inhibition screens to define host target-inhibitor combinations in controlling bacterial infections.

Here we propose to target biological pathways in the host cell to control bacterial infections and provide a strategy to define host target-inhibitor combinations through an integrated chemical and genetic approach and in an unbiased fashion.

The functional similarity between a host and a set of targets was determined as the mean of all single host-target scores.