The touring nature of the scheme is central and 11 regional galleries - Aberdeen, Bexhill, Colchester, Glasgow, Inverness, Middlesbrough, Cardiff, Walsall, Orkney, Belfast, Wolverhampton - have already signed up to host rooms.
Moderators can also make rooms 18+, in order to host rooms with topics not fit for minors.
Detroit's underground bellwether Omar-S headlines, while Futureboogie host room one and Horse Meat Disco go head-to-head with Classic Music Company in room two, with Classic's co-founder Luke Solomon DJing and NYC diva Honey Dijon playing live.
The original dubstep'n'garage genre-bender Oneman appears as a guest DJ, while Riddim Cottage host Room 2 for a bass-warped house arena, and Authentiq take over the brilliant tunnel space.
Skream, another disco convert, plays room one as do Simian Mobile, er, Disco, while evergreen Dalston radio station NTS hosts room three.
Canadian jack sculptor Basic Soul Unit supports with a live set, while the back-in-style Surgeon plays metallic, masculine techno in room two; rising deep house label RvS hosts room three with Alex Arnout, Asadinho and Paul Soul.
Oneman hosts Room 2, while dBridge is in Room 3. Entail Records Presents Okie Dokie Warehouse Party, Crucifix, SE1, 3 Aug, residentadvisor.net German rural techno don and sometime park ranger Dominik Eulberg makes a rare trip to London.
That precinct has around it a host of rooms that were used as lecture halls and seminar rooms and Greek and Latin libraries.
At the heart of the Old Town, Uerige boasts a host of rooms and bucketloads of character.
At launch, creators can only host 3 Rooms, Twitch says.
Along with a cleaner, much more sleek interface comes the ability to host huge rooms of listeners.
