Sentence examples for host of pathways from inspiring English sources
The human response to infection (including chlamydia) is to produce IFN-Ƴ, which, among a host of pathways, upregulates the enzyme indoleamine 2,3-dioxygenase (IDO) which depletes tryptophan.
Because p53 is responsible for regulating a host of pathways involved in maintaining genome integrity, including apoptosis, DNA damage repair, cell cycle regulation and metabolism (Freed-Pastor and Prives, 2012), mutations in this protein can have far-reaching effects caused by the dominant-negative mechanism outlined below.
Their report defines convergence as "the merging of distinct technologies, processing disciplines, or devices into a unified whole that creates a host of new pathways and opportunities" by combining life sciences, physical sciences, and engineering.
The excessive formation of ROS activates a host of signaling pathways including endoplasmic reticulum (ER) stress and cell death [ 3].
For example, studies in mice have implicated a host of signalling pathways as being critical in proper tooth eruption and development, including those involving the gene families Bmp, Eda, Fgf, Shh and Wnt, among others (3– 5).
This earlier work raised a host of potential pathways of influence on adolescent pregnancy and suggested the importance of exploring: socio-economic circumstances; connectedness to family and family setting; school influences and experiences; partner characteristics; knowledge levels; peer and adolescent norms; and community norms.
Differential modulation of host pathways could affect host cell survival or nutritional availability and subsequent Toxoplasma replication within the host cell.
Given some degree of overlap of host cell pathways required for successful replication of related viral pathogens, host-directed antiviral approaches also have the potential to move beyond the one-bug one-drug paradigm by broadening the pathogen target range of a chemical scaffold.
And we have a host of other predicted pathways, some of which have been used in this work to predict the functionality of some proteins.
Microarray analysis showed that Hcl1 affects a host of key cellular pathways in M. tuberculosis.
