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Previous genomic analyses of several filamentous fungi revealed their further potential as host microorganisms for bioproduction.
This enables us to engineer host microorganisms to enhance their innate metabolic capabilities or to gain new capabilities in the production of target compounds.
The present review shed light on the possibility of filamentous fungi as host microorganisms in the field of bioproduction in the future.
Together with our previous observation that MTG improves the growth performance of Lactococcus lactis under aerobic conditions, introduction of MTG into non-MTG-producing microorganisms thus can be considered as a useful approach to improve the physiological functionality of the host microorganisms.
This microbial system is promising not only for construction of larger libraries by employing other polyketide synthases and modification enzymes of various origins as members of the artificial pathway but also for efficient use of the potential of the host microorganisms.
The high-velocity jet stream created by blood passing through a defect in the aneurysm may allow platelets and fibrin to adhere to the partially denuded surface of endothelium, creating a sterile thrombus, though it can potentially host microorganisms [30].
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To select the host microorganism having the highest benzaldehyde lyase (BAL) production capacity, pUC18∷bal gene was transferred into four Escherichia coli strains.
The Gram-negative rod-shaped bacterium, Escherichia coli has been studied extensively on a fundamental and applied level and has become a predominant host microorganism for industrial applications.
Escherichia coli has been extensively used as a host microorganism for the production of recombinant proteins because of many expression advantages including simplified downstream processing, increased biological activity, enhanced product stability and solubility and authenticity of N-terminus of expressed proteins (Mergulhao et al. 2005).
Considering the efficacy of process design and its operation to meet those conditions, each sugar in the mixture needs to be utilized simultaneously by the fermentation host microorganism.
The natural resistance to the potential inhibitors in rice straw hydrolysate provides a strong advantage of L. brevis as a host microorganism of lignocellulosic fermentation.
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