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On the other hand, the host limits viral infection through differentially expressing the miRNAs that target essential viral genes [ 9– 12].
CydAB may operate when an excess of reductants, potentially coming from the host, limits metabolic turnover and a redox balance needs to be achieved [ 66].
The host limits the spread of such elements by transcriptional and post-transcriptional silencing mechanisms that reduce activity to tolerable levels [ 9].
Virulent microparasite strains have greater infectivity, higher tissue-degrading capacity and higher growth rates but are not generally selectively favored in nature if death of the host limits the population cycle of the microparasite (Pulkkinen et al. 2010).
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I halted the downloads because, like most Web site operators, I have a deal with my service provider, or host, limiting the traffic that I am allowed to generate without incurring further charges.
However, the side effects of viral carriers, such as recombinant viral vectors reverting to their original wild type or the possibility of adverse immune responses to the host, limited their further application [42, 43].
However, the high activity of the enzyme also often leads to an increased fitness burden on the host, limiting the predictability of its interactions and impact on host physiology, and potentially leading to mutations in the constructs.
In other words, not only does a more selective maize host limit the possible trajectories of MSV evolution by reducing the diversity of arising recombinants, but it also is more selective of maize-adapted polymorphisms.
Also, XcawΔ avrGf1 does not cause disease on sweet orange (Valencia and Hamlin) as shown in Figure 4, indicating that there are other host limiting factors in the Xcaw12879 genome or other virulence factors are required for XccA306 to infect different hosts.
We estimate that the recombination rate is low relative to mutation, and although we only tested for recombination within ATV, we expect that greater sequence divergence and lack of ecological opportunity (e.g., lack of geographic proximity or shared host) limit the amount of recombination between ATV and more distantly related samples.
In natural ecosystems, the genetic diversity of hosts limits the spread of epidemics in a wide range of conditions (Ostfeld and Keesing 2012).
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Justyna Jupowicz-Kozak
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