Your English writing platform
Discover LudwigExact(1)
The cricket paralysis virus internal ribosome entry site (CrPV-IRES) is a folded structure in a viral mRNA that allows initiation of translation in the absence of any host initiation factors.
Similar(59)
In healthy hosts, initiation of an innate and adaptive cellular immune response limits the severity of the infection to an asymptomatic and often self-resolving pulmonary infection in most cases.
Several RNA viruses have evolved remarkable strategies to recruit the host translation initiation factors required for the first steps in translation initiation by host cell mRNAs.
This reprogramming of both the biological and metabolic processes could be an attribute of the underlying defense response that is induced in the resistant host upon initiation of insect feeding along with the concomitant recognition of the avirulent gall midge biotype.
Most studies of interactions between HSV and host cell initiation factors have focused on eIF2α because of its established role in host defense.
Potyviruses can infect multiple hosts by relying on the host translation initiation factor 4E or its isoform iso4E.
For each of these viruses, host translation initiation factors 4E are required for infection in both Arabidopsis and in crops.
The IFIT family encodes genes induced by IFN treatment, virus infection or PAMP recognition and they confer antiviral protection through disruption of protein-protein interactions in the host translation-initiation machinery [ 31].
Smyth, M. J. et al. NKG2D function protects the host from tumor initiation.
Therefore, we can hypothesize that TEV-AT17 has enhanced its ability to infect A. thaliana Ler by improving the interaction of its VPg with the host's translation initiation factor eIF4E.
This inactivates MAPKs in the host, hindering the initiation of innate immune response and thus increasing the chances of survival of these pathogens.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com