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Inferring dynamic signatures of microbes in complex host ecosystems.
Gerber GK, Onderdonk AB, Bry L. Inferring dynamic signatures of microbes in complex host ecosystems.
Although these approaches, which treat data as static snapshots of microbial communities, can identify shifts in overall community structure, they fail to capture the dynamic properties of individual members of the microbiota and their contributions to the underlying time-varying behavior of host ecosystems.
This new approach aims at providing, by dedicated bioinformatic pipelines, a thorough description of pathogen proteomes and their interactions within the context of human host ecosystems, revolutionizing the vision of infectious diseases in biomedicine and approaching new viewpoints in both diagnostic and clinical management of the patient.
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This may reflect evolution to the host ecosystem.
It suggests that, by manipulating the internal host ecosystem, GI parasites may influence the external ecosystem by affecting the dynamics of another environmentally transmitted pathogen.
Disturbances within the host ecosystem may disrupt gut microbial community homeostasis, resulting in reduction or loss of some members of the intestinal community.
The discovery of this new radiation of parasites is accompanied by a heightened awareness of the many knowledge gaps that exist with respect to the general biology, epizootiology, and potential impact of mikrocytid parasites on hosts, ecosystems, and commercial fisheries.
Some of the differences can be attributed to habitat differences and some to differences between the two slavemaking-host ecosystems.
Microparasites (bacteria, viruses, fungi, protozoa) and macroparasites (helminths, arthropods) are important components of both external and within-host ecosystems [ 1].
However, eco-evolutionary approaches are not yet widespread and few attempts have been made to operationalize the ecological mechanisms at play in a tumor-host ecosystem.
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