Host death is essential for transmission, mature spores being released from the remains of dead infected hosts.
Host death is a function of species sensitivity to the toxins.
It is not clear, however, whether extraintestinal colonization occurs as a result of host death.
Cytokine levels must be tightly balanced during this response, because their overproduction may cause immunopathology and host death [18], [19].
This decrease in luciferase activity was reflected in visual symptoms indicative of host death in this host-microbe combination.
From those genes Hore_13740 is found in a neighborhood with an addiction toxin (Hore_1336a) and a "prevent host death" protein (Hore 13710).
This establishes complete dependence of the amoeba on symbiont supply of bacterial SAMS, with removal of the latter resulting in host death [37].
Further dissection of the regulatory activity of individual virulence factors on proinflammatory cytokines will likely illuminate mechanism of sepsis, septic shock and host death in B. anthracis.
Sea lice can compromise osmoregulation [12], induce behavioral changes that increase predation risk [13], reduce growth rates and, in sufficient numbers, result in host death [9], [14], [15].
In this case, uncontrolled parasite replication would rapidly lead to host death, minimizing the chances of transmission to a new host.
Previous studies had demonstrated that infection of µMT mice with the exclusive mouse pathogen Ectromelia virus (ECTV) led to virus persistence in internal organs and host death late in infection [8], [16].
