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The immunonephelometric methods that are used to measure serum IgG4 are susceptible to hook effect errors.
Recent report on fish hook effect by Zhu and Liow [Chemical Engineering Science 111(2014) 94–105] involves size analyses using laser diffractometry.
The "hook effect" observed for DSL binding to kidney hGGT1, is commonly observed in immunoassays and other multivalent binding assays at saturating levels of the analyte [ 52].
The optimized method is selective and specific for Aβ42, is free of the artifacts of non-parallelism, dilutional non-linearity, and hook effect, and is tolerant of significant blood contamination of CSF.
Dilutional linearity and hook effect was evaluated by spiking with Aβ42 calibrator solution to a combined level of 9,000 pg/mL into the LQC CSF solution and then diluting 2-, 5-, 10-, 250-,50-, and 100-fold in sample diluent with 0.033 % Tween-20.
Despite the strong accuracy and reliability of currently used hormone assays, some limitations should be reviewed, such as interference by autoantibodies, heterophile antibodies or macroprolactin and the hook effect.
Similar(25)
People don't want you to wander and start playing with another product, so it has a hooking effect.
The fish-hook effect is one of the most pronounced mechanisms responsible for air classification.
This phenomenon is more marked for the A type of the separator and leads to a higher fish-hook effect in the selectivity curve.
The discrete phase model was used to predict the effect of the geometry of the outlet on the collection efficiency and the fish-hook effect.
It is conclusively deduced by analyzing the results of CFD simulations, that the fish-hook effect is due to wall rebounding.
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