Therefore, only few patients can be identified with a homogenous clinical presentation for whom a therapeutic approach can be standardized.
More recently, however, widespread cognitive deficits have been described with variable memory performance between patients despite a homogenous clinical presentation (Helmstaedter et al., 2003; Elger et al., 2004).
However, previous researchers have also used physician service claims to sample patients with RA from rheumatology practices in order to calculate wait times on a smaller scale, and these studies may be subjected to similar biases (inclusion of early patients with RA with a more homogenous clinical presentation).
We also observed that the MAP-1B antibody response was very similar between animals vaccinated with ISA70+ER and ISA70M+ER emulsions, suggesting a more homogenous antigen distribution and presentation in these emulsions.
However, our findings are important because they demonstrate a link between infection-cause mortality and insufficient immune responses to HBV vaccination in ESRD, since these two clinical presentations involve homogenous but varied interactions between the immune, innate immune and the adaptive immune systems.
Therapy trials for these diseases are mostly hampered by heterogeneity of the disease manifestations and the consequent lack of patient groups with homogenous genetic background and clinical presentations (Suomalainen, 2011).
The results of this study present different symptomatic profiles of patients seeking treatment in a TMD clinic, who were classified by cluster analysis into four to six homogenous groups based on their clinical presentation.
The aim of this study was to simultaneously classify symptomatic patients diagnosed with a variety of subtypes of TMD into homogenous groups based on their clinical presentation and occurrence of comorbidities.
We tested VEGF bound in high density and low density to study differences between growth factor presentation in heterogeneous nanodomains and homogenous distribution.
Current classifications of BD rely on clinical presentations without any validating biomarkers, making homogenous and valid subtypes warranted.
