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Remarkably, even in a homogenous bundle the interaction between anti-parallel filaments now leads to a net contractile stress, see Fig. 4. The description of force and stress generation in filament bundles is stochastic in nature and based on microscopic interactions.
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In the presence of end-tracking cross-linkers, treadmilling can induce relative sliding between filaments of the same and opposite orientation, see Fig. 4. Simulating this dynamics analogously to the case of motor-induced filament sliding, we find again cases of stable homogenous bundles and cases where homogeneous bundles are unstable and complex dynamics emerges.
The areas treated with BNC are clearly visible, and the films are uniformly structured due to the relatively consistent fibre diameter, as well as by the smooth and homogenous fibril bundles (Figs. 4 left, 5 left).
DOI: http://dx.doi.org/10.7554/eLife.03348.005 10.7554/eLiFigure48.006 Figure 1 figure supplement 3. The chimeric neuronal SNARE protein folds into a homogenous SNARE four-helix bundle with an expected molecular weight.
Our results reveal that EN-actin is either dispersed in the nucleoplasm (homogenous EN-actin) or forms bundled filaments in the nucleus (EN-actin filaments).
In mature galls, such walls have uniseriate inner and outer epidermis, hyperplasic and hypertrophied homogenous parenchyma and collateral vascular bundles near the nymphal chamber (Fig. 1C).
The young leaves of P. cattleianum have uniseriate epidermis, homogenous chlorophyllous parenchyma with interspaced vascular bundles undergoing differentiation.
As a consequence, for a homogenous filament distribution, on average no contractile stress is generated in the bundle by this process.
Fourth, results from the single-molecule manipulation experiments are generally homogenous among different molecules pulled and consistent with correctly folded four-helix bundle structures.
POm band 1 is not homogenous but is characterized by regularly spaced triangular structures from which vertically oriented axon bundles extend toward the pia, forming the septa (Koralek et al. 1988; Lu and Lin 1993; Alloway et al. 2004; Kichula and Huntley 2008, Fig. 1 D ).
It seems homogenous".
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