Exact(2)
Once the sweep is finished, migration homogenises allele frequencies within each patch leading to flat curves while the barrier slows down homogenisation between patches.
The dynamics of homogenisation are analogous to the effects of gene flow: just as reduced gene flow allows variation to accumulate between geographically-separated populations, low levels of homogenisation between different chromosomal loci would allow the accumulation of different ribotypes (see Figure 7B-C).
Similar(58)
Low homogenisation frequency between rDNA arrays at different loci, together with strong selection pressures imposed on coding regions, would allow co-existence of repeats with identical coding but more variable non-coding regions.
The tubes were cooled on ice between each homogenisation step.
This hypothesis gained further support from Rada et al. when they compared sequences of rat and mouse MHC class I genes, and found evidence suggesting homogenisation of sequence motifs between distant loci on either side of the class II region [ 15].
All these data may be interpreted as a consequence of a balance between drift and homogenisation mechanisms acting on these subtelomeric genes.
The tissues were homogenised using an ULTRA-TURRAX TP18-100; IKA, Staufen, Germany) homogeniser, keeping the material during the homogenisation as cold as possible by returning the homogenate to an ice bath between short (approximately 15 s) bursts.
Disturbances were non-specific mass mortality events that varied in size between treatments: after thorough homogenisation, either 0.00001%, 0.0001%, 0.001%, 0.01%, 0.1%, 1%, or 10% of each population was transferred to a fresh microcosm.
Cells were lysed by three cycles of homogenisation for 1 min with cooling between each cycle in an ice-water bath for 1 min.
Despite the expected polymorphism, we found that the overall structure of RIFIN repertoires is conserved among clones suggesting a balance between genetic drift and homogenisation mechanisms which guarantees emergence of novel variants but preserves the functionality of genes.
These were homogenised three times for 30 seconds at 48 Hz, with cooling on ice between homogenisations.
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