Moreover, we could observe that animals which received fat grafts in osteosarcoma tumors were more homogeneous in their tumor progression as compared with control groups (SaOS2 and SaOS2 + cannula).
Endpoints related to disease progression were relatively homogeneous, with PFS, DFS, recurrence-free survival, and time to progression (TTP) being the most frequently used.
We therefore sought to evaluate outcome associated with bevacizumab continuation in comparison with non-bevacizumab therapy after initial bevacizumab progression among a homogeneous cohort of recurrent glioblastoma patients pooled from five consecutive single-arm phase II studies.
Finally, our model assumes that diabetes progression rates are homogeneous, in the sense that a severely obese person with active diabetes and an A1C of 8.0% has the same progression rates for diabetes complications as a nonobese person with active diabetes and an A1C of 8.0%.
We assume a homogeneous exponential distribution of time to progression from preclinical to clinical disease for given age.
Identifying reliable biomarkers for each symptom is useful, since each symptom category and progression to different severities is more homogeneous across patients than the overall depression rating, which can encompass completely different manifestations of the disorder.
Despite CML starts as a genetically homogeneous disease, it has been hypothesized that disease progression and clinical heterogeneity in CML are related to epigenetic factors including DNA hypermethylation.
Therefore, the aim was to explore the role of PP in the development of CVD and progression of diabetic nephropathy in a large, homogeneous and nationwide cohort of patients with T1D.
This includes RCTs targeting homogeneous patient groups with higher event rates for ARDS progression and early timing of trial enrollment (e.g. immediately after endotracheal intubation in the ED).
