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Allele specific amplification in a homogeneous format or combined to microarray hybridization are powerful approaches for SNP genotyping.
Colloidal AuNP is used to detect specific DNA sequences and single-base mutations in a homogeneous format.
Then, the RTLoader converts data coming from different kinds of instruments and with different source formats into a homogeneous format and then stores them in an RTDB.
Due to its unique features such as high sensitivity, homogeneous format, and independence on fluorescent intensity, fluorescence anisotropy (FA) assay has become a hotspot of study in oligonucleotide-based bioassays.
The assay can also be run in a homogeneous format with stain and permeabilization buffer added directly to the wells, post incubation, with no aspiration required.
The effect of running the assay in a homogeneous format on false positive or negative rates had not been fully evaluated at the writing of this article.
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A shrinking number of corporate owners control a growing share of the nation's radio stations and program them with proven, if homogeneous, formats.
Compatibility with homogeneous formats and the ability to assay small amounts of genomic DNA meets the exacting requirements of automated, high-throughput SNP scoring.
Here we report a strand-specific fluorescent homogeneous assay format for rapid polymerase chain reaction (PCR).
Here, we describe ResonSense® chemistries that use a simple linear fluorescent-labelled probe and a DNA minor-groove binding dye as either donor or acceptor moieties in a homogeneous assay format on the LightCycler®.
Together with homogeneous analysis format of "incubate-and-monitor" in the strategy and the simple and easy preparation of signal indicator used for the assay, the present CL assay for probing the enzymatic cleavage process of ssDNA and detecting S1 nuclease activity has displayed convenient operability with low cost.
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