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GLAD is one of many methods that have been developed for segmenting the genome into regions of homogeneous copy number.
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As part of the rDNA array, multiple, homogeneous copies of the ITS2 are presumed to exist within all eukaryotic organisms (ironically, making it an excellent barcode candidate due to greater ease of amplification).
It might be thought that the hundreds of highly homogeneous copies might contribute to genomic instability.
In plant genomes there may be from several hundred up to tens of thousands of highly homogeneous copies of each gene.
Their high copy numbers, homogeneous size, and high similarity within MITE families distinguish them from the typical defective nonautonomous transposons, which are usually unique copies (Feschotte et al. 2002; Guermonprez et al. 2008).
Finally, arrays with copies displaying different patterns in variation were exceptions that proved the rule: copies within homogeneous repeat structures conformed to a pattern indicative of concerted evolution, while others physically segregated from the repetitive region retained orthology with loci in other species.
But, the SNP within this homogeneous segment in term of copy number showed a significant different gene copy number between high and low expressing cells.
Our recursive lossless compression can be applied in a quantum multicast network where the source outputs homogeneous quantum states (many copies of a quantum state) to a set of destinations through a bottleneck.
In addition to differences in abundance among host genomes, several TE families presented genetically divergent but homogeneous populations of individual copies, indicating species-specific proliferation.
We searched for elements that share TIRs and subterminal sequences with those elements are devoid of transposase coding capacity and are present in high number of copies highly homogeneous in size and sequence.
Repetitive sequences with a low copy number are homogeneous and evolve slowly, whereas repetitive sequences with a high copy number are more heterogeneous and evolve quickly [80,81].
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