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For pedigrees with locus homogeneity selection of sample(s) for NGS is based upon the entire pedigree, whereas for families with locus heterogeneity samples are selected within each pedigree subgroup predicted to segregate the same causal variant.
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Deviations from homogeneity indicate selection for or against repeat regions.
Due to their homogeneity in selection of patients, we should consider VDX and TBG as the most important datasets in this comparative study.
In combination, these observations of relative homogeneity of selection within river systems, but heterogeneity among systems, could reflect a tendency for habitat attributes to differ more among systems or for genetic divergence to influence how populations respond to environmental conditions.
But not only does the OWS experiment skirt the problem of pluralism through self-selection, the ideological homogeneity of self-selection may make deliberation tend toward extremism, as Cass Sunstein's important work on deliberation and group polarisation shows.
This homogeneity in patients' selection was considered of great importance since RME treatment might have caused high variation in individual response.
For each sub-sample and each locus, we tested deviation from Hardy Weinberg equilibrium, variation in allele frequencies with exact homogeneity tests and selection using Ewen-Watterson neutrality tests as detailed before.
Our study demonstrates that pharmacogenetic pharmacodynamics studies require certain homogeneity in the selection of patients and therapy and that the presence of concomitant chemotherapeutic agents (such as irinotecan in this study) may confound the results by participating in the global pharmacodynamic events.
Across different pMHC combinations, there was no clear pattern or homogeneity evident in the selection for TCRβ usage, but Th2 conditions preferentially selected elongated CDR3α sequences.
This selection allowed homogeneity in body fat content and distribution between South Asians and Caucasians.
These proteins are also likely to be highly expressed at certain times and, given their role in protein folding, might be reasonable candidates for selection for homogeneity.
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