Sentence examples for homing property from inspiring English sources

In addition, it is not only a matter of triggering immune responses, but also of directing them to the target tissues; although these DC may enter lymph nodes directly and stimulate T cells, they are unlikely to give tissue-homing potential to those stimulated cells, as it is the source of DC and not the lymph node cells or stroma that determines the homing property of the stimulated T cells 11.

Dependent on environmental cues of lymphoid organs in which T cells and ILCs are activated, they could be also imprinted to acquire homing properties to other distinct peripheral tissues (Campbell and Butcher, 2002; Kantele et al., 1999; Masopust and Schenkel, 2013; Mora et al., 2003; Mora et al., 2005; Mora and von Andrian, 2006; Rott et al., 1997; Weninger et al., 2000).

Although filamentous and rod-shaped VNPs have increased tumor homing properties, most of the studies conducted in nanomedicine application have focused more on spherical plant virus (Biabanikhankahdani et al. 2016; Bruckman et al. 2014; Le et al. 2017; Shukla et al. 2013; Wen et al. 2012).

In addition, memory cells generated from these late transferred CD8 T cells adopt homing properties, characteristic of the CM subset.

This is suggestive of similar activation, cell adhesion and homing properties between DP CD21+CD27+ and SP CD21+CD27− B cells.

Therefore, in the presence of CD4+ T cells the localization of the CD8+ T cells to the abdomen in most likely driven not by antigen, but by cell-intrinsic homing properties.

Our observation that memory CD8+ T cells are poorly sensitive to the S1P agonist FTY720 further suggests that in addition to their homing properties, the egress of naive and memory CD8+ T cells from SLOs are differentially regulated.

Murine GC B cells overexpressing Bcl-2 under control of the Ig μ enhancer and therefore resistant to spontaneous apoptosis show different homing properties regulated by chemokine gradients in vivo.

Though the suppressor function of the two Treg subsets was found similar in in vitro tests, little is known how different are their homing properties, antigen specificities and the ability to expand in vivo in response to antigen stimulation and cytokines.

This observation was not reported with either ESC (H1 cell line) or iPSC differentiated in presence of OP9 stroma [3], [4], and suggests that our protocol may achieve the generation of hematopoietic cells with enhanced in vivo bone marrow homing properties [26].

Whether L. casei may use DC to behave as biological adjuvants for distinct subsets of Treg, including Foxp3+ nTreg or Ag-induced Treg and whether this probiotic may act by promoting their expansion, survival and/or homing properties remains an important issue to be further elucidated.