Sentence examples for homing capacity from inspiring English sources

Mst1−/− T cells also have defects in homing capacity [7], [9], and the Rap1-Rapl-Mst1 pathway has been previously suggested to play a role in controlling T-cell trafficking [10], [26].

Adoptive cellular gene therapy utilizes immune cells with specific homing capacity as "vehicle cells" to deliver therapeutic gene products locally after ex vivo retroviral transduction.

These results suggest that native MUC16 is also available in vivo to anchor Meso-TR3 to the tumor cell membrane and that this tumor homing capacity directly corresponds with an enhanced target cell killing mechanism, in agreement with our in vitro killing data.

The homing capacity of iPSC-ECs was assessed after systemic delivery into immunodeficient mice with unilateral hindlimb ischemia.

NPSC have been shown capable of immunoaltering the body's response and possess lung homing capacity.

This approach, often called active targeting, seems to imply that the conjugated ligand imbues the nanoparticle with homing capacity.

Instead of developing an alternative to pre-existing T cell manufacturing methods, the major goal of this study was to establish a stimulation and expansion platform upon which T cell quality could be easily improved to meet the required phenotypic characteristics, homing capacities, and potent effector functions for effective cancer immunotherapy (Rosenberg, 2008).

Taking advantage of homing capacities to the primary tumor site, MSCs have been used for the targeted delivery of immunostimulatory cytokines and chemokines, suicide genes, growth-factor antagonists, and oncolytic viruses after systemic administration [ 49].

wt and ADAM8−/− donor cells were detected in similar absolute numbers indicating that an absence of ADAM8 on progenitor cells does not affect their thymus homing capacities (Figure 4B).

TCM and TEM have different effector functions and homing capacities.

Also, some of the repopulating cells in UCB may have attenuated homing capacities.