Emerging new methodologies of computational biology, functional genomics and systems biology will allow us to shift the focus from understanding individual signaling circuits to a more holistic view of regulatory processes.
This initiative demands a holistic approach of understanding the regulatory networks and the complex mechanism underlying the C4 photosynthetic pathway and their systematic introduction into the rice genome.
Most importantly, our analysis revealed a modularized view of the aging process in cardiac tissue and established the ground for a more holistic perspective of the complex regulatory processes taking place in cardiac tissue during lifespan.
A comprehensive human rights due diligence requirement as a precondition for government contracts could bring these various requirements together, helping companies address individual regulatory demands in a holistic approach.
Our regulatory network provides a holistic background in which the important elements, relationships, and network motifs can be analyzed thoroughly.
ISU goes for the holistic approach, giving engineers insight into the regulatory climate behind satellite launches and lawyers a glimpse at the science underlying the space shuttle.
Here, a hidden semi-Markov model (HSMM) is implemented and tailored to handle multiple genomic profile, to better facilitate genome annotation by assisting in the detection of transcripts, regulatory regions, and copy number variation by holistic microarray or NGS.
Understanding the regulatory events occurring during this process in a holistic manner may provide insight into normal vascular development and maintenance, as well as vascular pathologies.
This article approaches the current EU policy regime in a more holistic manner and focuses on the exploitation of weaknesses in the regulatory framework by private firms, which has received little academic attention in the innovation and transition literature.
In this paper, we emphasise the need for a holistic approach to computer-assisted interventions where clinical, scientific, engineering and regulatory expertise are combined as a means of moving towards clinical impact.
