To facilitate the drug-screening process, we replaced quantitative analysis of immunostained images of randomly sampled neurons with holistic scoring by phase-contrast microscopy of populations of living cells, typically 1500 2000 neurons per ∼50-mm culture well.
For the rational design of nanomaterials and synthetic process, a holistic understanding of the phase equilibria, solvent effect on kinetics, interaction between nanomaterials and the fluid, and the transport phenomena in supercritical fluids is necessary.
The establishment of the National Crisis and Emergency Disaster Management Authority (NCEMA) in 2007 represented a paradigm shift from a "relief-centric" post-event management policy into a proactive, multidisciplinary, and holistic approach, covering all phases of mitigation, preparedness, response, and recovery.
Combining in depth analysis of tasks realization with a more holistic model of the entire use phase, this protocol can support the design activities.
The focus on reducing emissions is creating a shift from a use phase perspective into a more holistic approach using a life cycle perspective.
Still in its conceptual phase, the plan takes a holistic approach to understanding eelgrass, looking at the balance of the entire population.
This chapter presents a holistic view on speeding up the architectural design phase in which the above mentioned techniques are integrated in one single architectural design framework.
Methodology-wise, the trend observed is a continuation of the second phase, with the call for a holistic approach to the problem.
The last phase is what I like to call holistic awareness, when everybody understands that the new culture, in this case design, makes sense for the organization.
The findings are currently being used to support implementation of a phase II randomised clinical trial of a holistic intervention involving Future Care Planning for patients with advanced heart disease.
Multiple projects and methodologies are published every day but neither of them with the holistic approach that will assure complete success since the design phase.
