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Another study found 66% of Hispanic women living with HIV scored above the conventional threshold of possible clinical depression [ 45].
However, a point worth mentioning is that only 46.5% of those mothers who were tested for HIV scored perfectly although the questions mothers were asked in this study were very basic.
However, due to a lack of independence of the contributing factors their combined impact is not additive, and only a total of 55% of the PROQOL-HIV score variation could be explained by the complete covariate set.
Although significance of MOS-HIV score changes over time was not reported, PHS and MHS scores were significantly lower for those that experienced SAEs or ADEs compared to those who did not at most time points.
However, the fact that the combined covariate sets explained only 55% in the PROQOL-HIV score variation suggests the total score may incorporate facets additional to quality of life specifically related to HIV, and is assessing additional information from a patient perspective that cannot be adequately inferred from the usual sociodemographic or biological variables.
The global PROQOL-HIV score, as used in analyses, is a composite measure based on 38-items, comprising eight sub-scales (factors) that encompass the following domains: Physical health and symptoms (PHS), emotional distress (ED), health concerns (HC), body change (BC), intimate relationships (IR), social relationships (SR), stigma (ST).
Participants with severe difficulty sharing feelings had better MOS-HIV scores than those with low or moderate problems.
The trial found both no significant differences over time and no significant differences between treatment groups in MOS-HIV scores.
Consistent with the observed impact of clinical factors across most of the sub-scales, lower global PROQOL-HIV scores were strongly associated with occurrence of symptoms, depression or other comorbidities (Table 4).
Mean (SD) HIV knowledge score was 58 (12) and TB knowledge score was 33 (15), both scores out of 100.
A total HIV knowledge score was created by summing the scores for all questions.
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