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The analysis was completed online in ~2 seconds and produced an output file with 9411 common hits found in 49 out of the 50 screens.
The results show 317 hits found in Metrabase that exhibit structural similarity to the catechin chemical structure.
The F (N = 500) values for the 46 tested cases with the hits found in the top 10,000 decoys are listed in Additional file 1: Table S3.
Indeed, whereas Surflex yielded the best results for Cdk2 with 3 hits found in 22 molecules, it ranked poorly the only hit identified for Hbp, and on the contrary, Glide, with which no hit was identified for Cdk2, ranked rather well the hits of Cn (Table 1).
Based on the available literature, 38% of the hits found in this study are already found and reported as confirmed in vivo tyrosine phosphorylation sites in human proteins.
When searching for ER QTL within the list of GR hits found in both males and females (involving 78 transcripts), we tested five significance cutoffs for defining an ER hit, spanning a wide range of strengths (see Materials and Methods).
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All sequences which resulted in "no hit found" in the BLASTX results were subsequently translated in all six frames and appended to the end of the 'best peptide' file.
Hits found also in bacteria were specially checked for the presence of a poly A+ tail.
Most of the hits found only in MAIZEWALL were secondary cell wall-related genes including phenylpropanoid and lignin biosynthetic genes.
In Fig. 5b e we reported the number of hits found for each target in the n test best-ranked molecules from each docking program.
The best hits were found in Punctularia strigosozonata (2,536 hits), followed by Serpula lacrymans (909 hits) (Additional file 1: Figure S3B).
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com