Sentence examples for hitherto involved from inspiring English sources

For Keys and Gray are to become the new hosts of Talksport mid-morning rantathon, which has hitherto involved Mike Parry and Mike Graham fulminating against everything from political correctness gone mad to political correctness gone mad.

Designs of highly modularised, prokaryotic AND logic devices have hitherto involved the use of multiple plasmids [ 10, 12, 16, 36, 37].

A further set of factors, not considered hitherto, is involved in the generation of protein heterogeneity in the cell.

We have unravelled a hitherto unknown mechanism involved in epithelial patterning, which is also conserved in the pectoral fins – evolutionarily recent appendages that are homologous to tetrapod limbs.

Because this outbreak involved hitherto unrecognized equine manifestations with predominant neurologic disease in the relative absence of respiratory signs, equine case definitions have been revised to include either respiratory or neurologic manifestations or both (21 ).

Among the various cellular players, fibroblasts, macrophages, T cells and B cells especially have been in the scope of interest of worldwide rheumatology research – which has identified numerous hitherto unknown mechanisms involved in the activation and proliferation of these cells and their interaction with other articular components.

But Alibek does not believe that the test involved a hitherto unknown strain but rather India-1967 (also known as India-1), a strain that the Soviets have long been suspected of using in their bioweapons program and whose DNA was sequenced in the early 1990s.

Perhaps not surprising, but none the less exciting, are emerging examples of the involvement of hitherto unidentified genes and mechanisms involved in resistance.

This unexpected trend can be explained by exploring two mechanisms of drop breakage at the impeller, other than the hitherto recognized mechanism involving turbulent inertial stresses.

This also implies that cohesion does not involve hitherto uncharacterized interactions between cohesin rings (Zhang et al, 2008).

In conclusion, we have shown that MT1-MMP is essential for the invasion of UCC cell lines, and involves hitherto unreported mechanisms.