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Hitherto, future studies are warranted to assess whether hyperglycemia-induced TXNIP/TRX/ROS biology is a prerogative of MDA-MB-231 cells or it extends to other breast cancer-derived cell lines independently from their hormonal receptor status (estrogen receptors) or signaling pathways (ras mutations, p38 MAKP milieu, etc).
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Our theoretical model can inform future empirical research, which hitherto lacked a common representation framework for organization design.
These discoveries will help shape models of how the hippocampus and PFC support navigation, memory and future simulation, which have hitherto generally neglected the importance of entering new regions of space and the processing of topology.
Opponents will be watching those hitherto lightly regarded fists a little more closely in future.
This conclusion opens up new prospects for future fieldwork in an area that was hitherto essentially neglected.
For C. glutamicum, the function and the regulation of expression of these antisense RNAs is hitherto unknown, but represent an interesting research target for future studies.
The present health organisation requires that the work hitherto done by the Trust and the Commission shall in future be undertaken partly by a Ministry of Health committee, and partly by the regional hospital boards.
Second, model biases were not corrected, and third, future changes in the land surface characteristics were hitherto almost never taken into account.
The apparent recent movement of a virus genotype previously associated with virulent ASF in eastern Africa to western Africa, where the viruses have hitherto always been classified in p72 genotype I, indicates the possibility of future outbreaks of disease caused by novel viruses in western Africa.
The repertoire of protein scaffolds hitherto recruited for combinatorial protein engineering purposes will probably be further expanded in the future, including both additional natural proteins and de novo designed proteins, contributing to the collection of libraries available at present.
When Oscar Pistorius donned a pair of carbon-fibre blades to compete alongside able-bodied athletes at the 2012 Olympics, he had ceased to be a disabled athlete; instead, he offered us a glimpse of a "superhuman" future where Paralympians aided by bionics or performance-enhancing drugs might set hitherto unimaginable sporting records.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com