This hitherto unrevealed extensive variation in B-cell antigenic regions suggests a still undisclosed complex scenario of dynamic antigenic profiles for this unavoidable pathogen's antigen, likely representing new neutralization escape mutants that continue to co-evolve with the human host.
According to one of the hitherto most extensive reviews of predictors of long-term sick-listing for spinal pain, prior sick-listing for all diagnoses has been insufficiently studied [ 1].
The long-awaited authorized biography of Samuel Beckett by James Knowlson was a much-praised work that combined biography with literary criticism and featured a hitherto unknown but extensive correspondence between Beckett and an American woman with whom he had had an affair in the 1950s.
In this paper, first the existing model is briefly presented, followed by a review of the design and implementation of a series of experiments conducted to study the performance and behaviour of the SE system and to develop extensive, and hitherto unavailable, operational data.
It became clear after the Gulf war that the WMD ambitions of Iraq were far more extensive than hitherto thought.
The electrochemical storage of energy in automobiles faces the possibility of a major change, in that the electrical systems planned for vehicles are expected to be far more extensive than hitherto.
One of the most striking observations about the roster of genes occupied by Rbf1 was its extensive and hitherto unappreciated occupancy of genes involved in essential, conserved signaling pathways.
He was the last and most extensive participant in a hitherto unnoticed line that went back to early-19th-century Vienna.
Head also insisted on the need to study the condition of aphasic patients in a much more intensive and extensive way than had hitherto been attempted.
This "erratic extensive elongation" (EEE) of telomeres is a hitherto unrecognized phenomenon in non-neoplastic cells, and females are more successful in this respect.
