Not only did it define an area of cultural enquiry that had hitherto barely existed; it also established a context that no discussion of the new wave of late-1950s northern writers - John Braine, Alan Sillitoe, Stan Barstow, Sid Chaplin - could ignore.
"The 500 TW shot is an extraordinary accomplishment by the NIF Team, creating unprecedented conditions in the laboratory that hitherto only existed deep in stellar interiors," said Richard Petrasso, a physicist at the Massachusetts Institute of Technology.
Hitherto, Tigerland has existed as a world unto itself, protected, as Kushal had pointed out, by its inscrutability — impenetrable, secretive, inviolate.
His 14 majors were racked up at an unprecedented rate during a decade in which he redefined what it was to hit a golf ball, introducing an athletic dimension that hitherto had not existed.
Eventually Quentin created a path from his front door into and around his room, a path that hitherto had never existed.
Moving, or rather being pushed, closer to China amidst confrontation with the West, Moscow has lifted formal and informal restrictions on Chinese investments that existed hitherto and begun to actively court Chinese capitals.
From this and other studies, it is reasonable to assume that a great variety of hitherto undetected CoVs exist in wild bird species.
This case illustrates that there may exist hitherto unknown connections between tubular and glomerular dysfunction in patients with nephrotic syndrome.
5 7 However, the actual predictive value of these factors is low, suggesting that other factors, hitherto unidentified, must exist.
Thus, we conclude that in marked contrast to the hitherto known pheromone-binding proteins, GP-9B undergoes phosphorylation and thus existed in two forms, phosphorylated GP-9B (pGP-9B, observed MM 14,810 Da) and dephosphorylated form (GP-9B, observed MM 14,730 Da).
