Sentence examples for hitherto difficult from inspiring English sources

Like many women artists, Muriel Spark found her voice comparatively late in a hitherto difficult life.

Inhalation drug delivery offers a new avenue to scientists for understanding and enabling compounds hitherto difficult to deliver via the traditional routes.

It was hitherto difficult to determine the phenotypic sex of embryos and young larvae, because they do not show any sexual difference in morphology.

It may also be possible to grow clinically derived samples, hitherto difficult to sustain, using osteopontin and so use it as a vehicle in the downfall of cancer, which would be a fitting role.

These traits include other biosynthesis genes affecting ripening or fruit quality, and constructs for herbicide, virus and insect resistance that were hitherto difficult or not possible to breed using a more traditional approach (Schuch et al., 1991).

Web technology delivers information and research data that have hitherto been difficult for the non-specialist to access and have therefore been under-exploited.

The latter charge, introduced in the 2005 Gambling Act, is untested in a British court and could provide prosecutors with a way to deal with sporting corruption cases for which obtaining convictions have hitherto proved difficult.

The original 2nd-ASAM presented in this work should enable the hitherto very difficult, if not intractable, exact computation of all of the second-order response sensitivities (i.e., functional Gateaux-derivatives) for large-systems involving many parameters, as usually encountered in practice.

To try to improve its predictions, the NHC has just added a new weapon to its armoury a Gulfstream IV jet, bristling with weather surveillance equipment, which can fly 12 1/2km above the earth.In this section An act of God The unkind child A log in the wind ReprintsThis means it is now possible to collect data from a layer of the atmosphere that has hitherto been difficult to monitor.

A major focus of the ATOL plastid genome sequencing project is the use of whole-chloroplast genome sequence data to determine the evolutionary relationships among the basal lineages of eudicots, which have hitherto proved difficult to resolve [ 23].

I found it a very readable informative book covering a wide range of topics both surgical and nonsurgical, and providing a wealth of information which hitherto was difficult to find in one place.