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The "central hit strategy" selectively targets central nodes/edges of the flexible networks of infectious agents or cancer cells to kill them.
While we can expect a few successful generics, it's clear that most applying for these types of domains are using a "roll the dice and hope for a hit" strategy.
I was appointed by Secretary Gee with the charge to improve the quality of healthcare for the state of Louisiana, develop a statewide HIT strategy that would help us achieve the vision of quality, transparency and accountability, and address the health needs of the new expansion population.
The reciprocal best BLAST hit strategy (RBH), used as first step for most BLAST-based orthology detection methods, displays a low FP error rate (8%), but its inability to recognize many-to-many or many-to-one co-ortholog relationships results in a high FN error rate (30%), as previously expected [4].
Resulting effects rely again on the multiple pathway hit strategy built into MB.
The reciprocal best hit strategy of sequence similarity comparisons was used here to distinguish orthologous from paralogous genes.
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We design three different Human Intelligence Task (HIT) strategies and report high inter-annotator agreement between non-experts and expert annotators.
The Hollywood Reporter quotes a Gaga spokesperson who explains the sleeper-hit strategy was intentional, with screenings centred round a major Tokyo cinema, leading to packed theatres and mushrooming buzz.
In the optimal hitting strategy, batters "track the ball with smooth pursuit eye movements and fall behind in the last five feet".
The gene content of CroV and that of other NCLDVs were compared using the best reciprocal BLASTp hits strategy, allowing the detection of pairs of ORFs that are reciprocal best hits for each other [37], [38].
However, if not the reciprocal best-hit strategy but the uni-directional best-hit search was applied, 28 organisms were found to have homologues to LuxP.
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