Sentence examples for hit pathway from inspiring English sources

Fatty acid biosynthesis was the second top hit pathway.

The top hit pathways in pathway analysis with p value ≤0.05.

MP: Matching pairs; EC: edge correctness; LCCS: Largest common connected subgraph; MF: Molecular function; BP: Biological process; CC: Cellular component; OP: Orthologous proteins; HP: Hit pathways; PAC: Pathway average coverage.

Most known tumor suppresser genes are associated with monogenic dominant cancers following a two-hit pathway.

Previous studies have revealed that mice deficient in CHOP or in the PRR's SRA, CD36, TLR4, or TLR2, are markedly protected from macrophage apoptosis by this two-hit pathway [9], [24], [27], [46].

Interestingly, there appears to be a "two-hit" pathway in which animal priming with first airway disease (by administration of intratracheal Aspergillus) or skin disease (by subcutaneous injection with ovalbumin) is needed to induce esophageal eosinophilia.

"Why hit one pathway so hard?" asks Hassan.

A comparison of the top hit KEGG pathway generated from both methods was presented in Additional file 9, where a similar hit pattern of the over-representative genes in both methods were found.

CNetA and BLASTA hit 11 pathways with PAC larger than 29% in total 12 KEGG pathways.

Heath uses "targeted drugs to hit signaling pathways, like those driven by EGFR, that maintain the tumor and help it grow," he says.

There is also a rationale for combining targeted agents that hit complementary pathways, but to date there are few confirmed examples of combined targeted agents being better than single agents, and toxicity is often increased.