Sentence examples for hit alters from inspiring English sources

In these instances - in line with the model of two hit inactivation - one mutational hit alters the methylation pattern of one allele and the second allele is either lost or inactivated by a structural mutation.

In such a model we hypothesize that an inherited allelic defect (or possibly a group of allelic defects) constituting a first "hit" alters palmar fascial physiology in DC patients, but not sufficiently so as to lead to the DC nodule/cord phenotype.

SEVEN GUITARS (1948) A blues musician's unexpected hit song alters the lives of his sidemen, friends and lover.

If Manning stays, in a game much more brutal than baseball or golf, might he take a hit that alters his life and colors his legacy?

This could be done by creating a library of derivatives in which the building blocks used bear some resemblance to those employed to construct the primary hit, but alter the steric or electronic nature of that module somewhat.

With his two hits, Gonzalez altered a postseason marked by spectacular fielding and virtually no hitting.

These hits can alter biochemical pathways until a pathological threshold is reached, which appears clinically as the onset of dementia.

Radiation can induce genetic or epigenetic change in a single-hit cell altering the internal homeostatic control of transcriptional regulation of the genome, thus may generating additional hits.

The P values and the order of the hits are altered when considering smaller reference sets (Appendix 1 and Appendix 3).

More than one hundred hits that altered the abundance of either p53, Mdm2, or both were identified in the primary screen.

Pharmacodynamic biomarkers are used in preclinical studies and phase 1 trials to confirm that the drug hits the target and that hitting this target alters the pathophysiological mechanism.