Historically, overall survival (OS) has been regarded as the "gold standard" of endpoints.
Historically, the survival of your race, your tribe, or your brood partly depended on weeding out the weak, yes, so that they died and didn't procreate.
Beetles appeared 285 million years ago and have since occupied nearly every available ecological niche, and it is this sustained diversification in a variety of plant associated niches, combined with the historically high survival of beetle lineages, that is thought to have led to their current success [19], [20].
However, there can be significant toxicity associated with these combinations and historically, median survival has been 6 9 months.
Historically, marine survival was lower in the early-migrating fish, suggesting that the shift in adult migration timing might have negative consequences at other life stages.
Jared Diamond [ 15] has recently argued that, historically, the survival or collapse of societies can be explained from the perspective of their interactions with the ecosystem.
Historically, graft survival rates in PTA recipients had trailed the rates in SPK recipients, in part because of the absence of a simultaneous kidney transplant in PTA recipients.
These new results suggest that arsenic exposure in this population may have historically reduced survival and reproduction rates enough that it led to a strong selection for individuals carrying arsenic-resistant haplotypes.
Owing to the historically short survival time in patients with NSCLC, reports of SRE frequency in this population are limited to data from the placebo arm of a large clinical trial [ 28, 29], retrospective studies from Asia [ 30– 32] and a Serbian bone scintigraphy study [ 33].
I'd like to think we easily alarmed types are historically better at survival.
