Sentence examples for historically studied from inspiring English sources

Historically studied for their effects as pathogens, recent advances have incorporated viruses as substrates for chemical modification, materials development, and therapeutic design.

These enzymes have been historically studied and engineered to make un-natural polyketides for drug discovery, and have also recently been explored for synthesizing biofuels and industrial chemicals due to their versatility and customizability.

Our system should encourage researchers to leave their 'disease ghettoes' and break interdisciplinary barriers by linking entities that have been historically studied by different sub-disciplines of virology, mycology, parasitology, mycobacteriology, immunology and dermatology, among others.

The regulation of the HSR has been historically studied as a cell-autonomous process in yeast and metazoan tissue culture cells, in which HSF-1 is activated by titration of inhibitory chaperones through the accumulation of misfolded proteins (Ananthan et al., 1986; Morimoto, 1998; Åkerfelt et al., 2010) (Fig. 2A).

Recent research has yielded increasing evidence that certain PCB congeners not historically studied for adverse health effects appear to have endocrine-disrupting effects and/or the ability to interfere with the function of cellular receptors that play a vital role in regulating neural development and function.

Such samples provide a context from which to historically study adhesives, adhesive formulation and polymer degradation and to map changes in conservation practice in the selection and application of these materials.

Historically, studying the biochemical role and probing the unique structure of CuA centers have not been easy due to complications arising by overlapping spectroscopic features of other metal centers present in the native proteins containing the CuA center.

Historically, study of their function focused on oxygen as a reversibly bound ligand of the ferrous form of the protein.

Historically, studies on feature extraction for chord recognition started with the introduction of chroma features, a.k.a., pitch class profiles, in 1999 by Fujishima[3].

Historically, studies of the effect of caffeine on people's driving abilities when drunk (in the lab, not on the roads) have had contradictory results.

Historically, studies of wind resources have however differed in their incorporation of physical limits, land availability and economic constraints, resulting in a wide range of harvesting potentials.