Historically, effects of the vitamin on the cardiovascular (CV) system have been proposed and demonstrated in the literature, including benefits on serum lipids.
There are no data yet on the effects of the recession on measures of inequality, but historically the effect of downturns is to increase, not decrease, class polarization.
Historically, wall effects in small-scale SBCR reactors (diameters less than 30 cm) have presented many challenges with regard to interpretation of kinetic/conversion data for process scale-up.
Historically, the effects of CR have been viewed as being associated with the aging process [ 1- 3].
"Say you're dosing animals with a chemical where, historically, an effect has not been seen below a dose of ten milligrams per kilogram," Bus explains.
A key source of evidence that present-day selection can override historically contingent effects comes from the repeated evolution of similar adaptations in different taxa.
Historically, side-effect profiles have limited the use of targeted AR therapies for breast cancer [ 21], but a more vexing problem has been the inability to predict response in pre-clinical models.
To further benchmark our findings, we also estimated the expected distribution of repeated adaptive evolution if its occurrence was unrelated to the phylogenetic separation of taxa (i.e., historically contingent effects on the outcome of adaptation were absent).
The demonstration of adverse health effects has historically preceded effective pollution control measures.
Because of this, placebo effects have historically been discounted as effects that aren't medically "real".
Historically, the Study effect has been considered a fixed effect not because of a strong argument that such effect is indeed fixed but because of our prior inability to efficiently solve even modest-sized mixed models (those containing both fixed and random effects).
