Sentence examples for historical control data from inspiring English sources

To assess the antifracture efficacy of this regimen, data collected in the 2CDM study were analyzed using historical control data matched for key clinical characteristics from 2 placebo-controlled trials.

Recommendations for the use of historical control data for the interpretation of avian reproduction studies are made.

Further, we did not randomise between an intervention group and a control group, but compared our current cohort with historical control data, which can lead to bias.

The use of appropriate historical control data may provide an alternative design to assess fracture effects in osteoporosis trials for which simultaneous placebo-controlled data are unavailable.

This finding does not represent a toxicologically significant effect because rats on the EO diets gained more weight during the course of the study than historical control data on this strain of rats.

In this paper, we propose a Bayesian clinical trial design that uses a Markov multistate model along with a power prior for the parameters which incorporates historical control data to estimate transition rates among two randomized groups as defined by the model.

Logistic regression analysis was used to compare the JIA ACR 30 data with historical placebo data and historical active control data: ORs and corresponding 95% CI were computed for the overall population and for each of the JIA categories.

These survival rates were considered superior to historical control survival data.

The usefulness of weighing organs in toxicity studies includes their sensitivity to predict toxicity, enzyme induction, physiologic perturbations, and acute injury; it is frequently a target organ of toxicity; it correlates well with histopathological changes; there is little interanimal variability; historical control range data are available [ 30].

The JIA ACR 30 response rate in this study was comparable with the historical active control data 17 overall (OR 2.0; 0.5 to 8.3) and for the three JIA categories, eoJIA (OR 2.0; 0.4 to 9.8), ERA (OR 1.5; 0.2 to 10.4) and PsA (OR 2.3; 0.2 to 21.3) (figure 2C).

Compared to historical controls, our data suggests that glycemic control improves with intermittent feeding (significantly lower percentage of patients with blood glucose >180 mg/dl).