Sentence examples for historic difficulties from inspiring English sources

In retrospect, this finding may account for historic difficulties in obtaining pure mouse HSC populations and the low yields accompanying more promising approaches.

Their results indicate that the historic difficulties in classifying these ferns have been due to a combination of evolutionary stasis, with disparate groups appearing to be closely related due to shared ancestral morphologies, and evolutionary convergence, with the repeated evolution of similar features.

Ryan defined "default" as only the failure to make a bond payment, and said his bill -- which passed the committee on a party-line vote of 24 to 15 -- was a sensible backstop, given Congress' historic difficulty with increasing the debt limit.

Given the historic difficulty in developing analytical methods for treating mutation/selection balance in changing environments, we chose instead to employ a computational approach.

Because of the historic difficulty of distinguishing neoplastic and non-neoplastic forms of C-cell hyperplasia in both rodents and humans, the diagnostic significance of C-cell hyperplasia is unclear.

Conversely, traits such as fat thickness, docility, and heifer pregnancy rate have not been as intensely selected as growth traits, due to the differing breeding objectives of beef producers, genetic antagonisms constraining selection response, and the historic difficulty in collecting field data to allow the development of EPDs for these traits.

However, historic and continuing difficulties in purifying, maintaining and/or expanding tissue-specific stem cells in vitro has hampered development of novel therapeutic approaches using these cells.

Please, let this historic March proceed without difficulties!

Despite the inherent difficulty in characterizing historic diets in evolutionary studies, there is evidence supporting recent and continuous diet-driven selection in humans (58).

The MPs said the difficulties were linked to historic debt, bad management and the current drive to make savings.

"People should see the historic significance rather than trying to see difficulties in it," he said.