There are also hints of benefit from vitamin K, an essential nutrient found in cruciferous vegetables (broccoli, kale, cabbage and the like), which are good for health in general (unless you take blood thinners).
Larry Biegelsen, the analyst who covers Abbott for Wells Fargo, has said that he thinks TriCor will fail in Accord too, although there may again be some hints of benefit.
In April, another team told a medical meeting that its experiments in gene therapy for Parkinson's, which delivered a different gene to a different part of the brain, also appeared safe and gave a preliminary hint of benefit.
Some suggest the disease is not being targeted early enough [ 68], noting that in animal models anti-Aβ approaches clear hyperphosphorylated tau aggregates when given to young, but not old, animals [ 69] and, also, detailed analysis of recent trials have shown hints of treatment benefit in individuals treated early in disease [ 57].
But along with known benefits of organic food for the planet, we have more and more hints of potential health benefits as well.
Although there was a significant benefit in this experiment, there was no hint of a benefit in Experiment 6, which was an exact replication except that the target prevalence was increased from 25% (Experiment 5) to 50% (Experiment 6).
While NICE makes a recommendation regarding reimbursement based on the (combined) appraisal of clinical and cost-effectiveness, G-BA/IQWiG quantify the additional benefit and its results certainty (e.g. proof, indication, or hint of additional benefit).
"We don't think there is a hint of a benefit," he said.
Still, it would have been nice to see a hint of a benefit for checkups in this analysis, given how much effort and time is invested in screening.
