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But the overpowering smell of fresh paint inside hints of activity soon to come.
Another value of these technologies is that they can help the military monitor a broad area for hints of activity, and then zoom in for a detailed picture of a potential target.
The clinical data are just slowly maturing and hints of activity are seen in the BRCA-mutation cancers and triple negative breast cancer (TNBC).
Response rates are difficult to interpret in phase I studies where they can be only considered as complementary observational data looking for hints of activity.
These are vital, for example to provide hints of activity of new agents in very rare cancers, which could be tested within industry-sponsored trials in case of a positive result from early low-cost studies.
In addition, screening of new drugs in rare cancers is by definition less likely to happen, since phase I studies will privilege frequent cancers (more likely to be enrolled in comparison to any single rare cancer in any phase I study), and hints of activity from the phase I setting will be therefore lacking in rare cancers.
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These early hints of activities have led to anticipatory excitement for this class of agents.
Maybe I can hear the distant sound of a badly-tuned radio or the feint echo of young laughter under the virtual tide's hissing swell, a just-audible hint of activity on the edge of the cyber sea.
Hint of activity was apparent only with low-dose NGR-hTNF.
However, a hint of activity was apparent only with the lower dose.
Even though antitumour activity assessment was not the primary end point of this small-size, single-arm combination study, some comments about hint of activity are warranted (Table 2 and Figure 2).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com