During the test the intrados hinges opened initially for an angle β = 56.25° (Fig. 11), and did not move at the displacement increasing.
When this structure is under mechanical tension, one of the hinges opens along the tensile axis, whereas the other hinge expands in the lateral direction, resulting in a negative Poisson's ratio in the out-of-plane direction [2].
The two lateral hinges opened the cervical canal like a French-door with plastic deformation/greenstick fracture of the troughs and a spacer material (bone graft or bone graft substitute) was placed in between the opened spinous processes to prevent re-closure [18].
According to both the strong and weak versions of the ring model, cohesin would not be able to associate stably with chromatin if hinges opened even transiently in postreplicative cells.
Set the door on a solid surface, such as a workbench, and install the hinges at the location you marks, being sure to check that the hinges open the correct way.
But the one on the left has a telltale curb cut, and what appears to be a fixed bay is actually hinged, opening sideways on a sliding track.
The ring model predicts that sister chromatid cohesion would be lost by transient hinge opening.
They suggest that hinges participate in a major conformational change during S phase, possibly hinge opening, linked to acetylation of Smc3's NBD.
Of note, if ATP hydrolysis indeed led to hinge opening for DNA entry, head dissociation would have to be actively prevented, or else DNA would merely pass through both hinge and heads but not become entrapped.
Ligand binding in hDHFR occurs through a hinge opening motion of the adenosine subdomain relative to the loop subdomain, rather than from the conformational sampling of the Met20 loop as in ecDHFR.
